Only 31% of the difference between RN PCx-PG and 46% of the difference for LAB PCx-PG could be accounted for by the variables tested. RN PCx values were higher than PG values (mean = 4.9%), while LAB PCx results were lower (mean = -5.2%) than PG values. There were 475 samples analyzed from 132 patients. Data were analyzed by simple and mixed-effects regression analysis and by analysis of a receiver operator characteristics (ROC) curve. Glucose measurements were taken at the bedside on the glucose meter (RN PCx) as well as in the laboratory on both the glucose meter (LAB PCx) and the laboratory analyzer (PG). Demographic information, sample collection information (nine variables) and a recent hematocrit value were recorded for each sample. In this prospective study, all patients in the neonatal intensive care unit who had a plasma glucose test ordered were eligible to participate. In this study we investigated potential reasons for this inaccuracy and established a cut off value for confirmatory testing. Glucose meters however, lack the same accuracy as laboratory instruments for glucose measurement. Point of care (POC) glucose meters are routinely used as a screening tool for hypoglycemia in a neonatal setting.
#Istat glucose range pro#
In conclusion: the Precision Xceed Pro is suitable for use in neonates if a blood sample is directly applied from the heel onto the strip (not using a capillary). When using a capillary to obtain a blood sample, results from the Precision Xceed Pro were significantly higher compared to the iSTAT cartridge glucose test results (Δ= 0.19 ± 0.37 mmol/L). Results with the Precision Xceed Pro correlated well with those by the ABL blood gas analyzer and with those by the iSTAT glucose cartridge (R = 1.00 and R = 1.00, respectively). In this study, we performed Precision Xceed Pro glucose measurements on capillary neonatal blood samples (obtained directly from the heel of the neonate) and compared the results with a well validated routine glucose assay. Glucose test strip measurements can result in false results due to increased hematocrits in neonates. It is important to use a point-of-care (POC) glucose system in neonates that is specifically validated for these subjects.
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